BioBarrier PM

Pericardium Membrane – Key features

• Excellent adhesion to soft and hard tissues
• Higher flexibility than tendon-derived membranes, with good formability in curved areas
• Source: bovine pericardium
• Composition: natural Type I and Type III collagen
• Structure: natural, organized collagen fiber arrangement with the body's natural cross-links
• Storage conditions: 15–30°C
• Shelf life: 3 years after production date
• Longer resorption time than BioBarrier CM due to preservation of the natural collagen structure and cross-links
• High mechanical resistance to tearing, easy suturability, and space maintenance for covering the bone graft site
• Natural collagen structure with biological cross-links similar to the body's natural membranes
• Available in two thickness models: thin 150–300 µm; thick 500–1000 µm
• Rapid wetting and high foldability to enable secure fixation in difficult areas using screws, tacks, and suturing in all directions

BioBarrier® PM – Thin (150–300 µm)

BioBarrier® PM – Thick (500–1000 µm)

CM vs PM – how to choose

BioBarrier CM and BioBarrier PM are two resorbable collagen membranes of animal origin used in the reconstruction of soft and hard tissues. They differ in origin, physical properties, and clinical applications, so selection depends on the surgical indication.

BioBarrier CM is prepared from bovine Achilles tendon and contains high-density Type I collagen without chemical cross-linking. It has a dense structure with a thickness of 300 µm and, due to higher swelling after wetting, is considered suitable for sinus-region surgeries, periosteum, or areas where additional membrane volume is needed to maintain space. It is particularly preferred in procedures such as sinus lift or subperiosteal grafting because it can create a greater volumetric effect; however, due to lower formability it is less recommended in techniques such as the Sausage technique.

By contrast, BioBarrier PM is prepared from bovine pericardium and contains Type I and Type III collagen with a natural structure and natural biological cross-links. It is available in two thicknesses (thin: 150–300 µm; thick: 500–1000 µm) and provides very high flexibility, greater tensile strength, and excellent suturability. Therefore, it is more widely used in procedures such as cardiovascular reconstruction as a patch, dura mater repair in neurosurgery, orthopedic and soft-tissue surgeries, and graft-volume support techniques such as the Sausage technique.

In terms of resorption time, BioBarrier PM—because it preserves its natural structure—resorbs more slowly (about 8 to 12 weeks) compared with the tendon-derived type. It is also considered more suitable in environments requiring higher mechanical stability, desirable flexibility, and longer durability.

Special PM applications

Specialized applications of BioBarrier PM

• Open-heart surgery: pericardial reconstruction and prevention of adhesions between the heart and sternum
• Vascular surgery: as a covering around synthetic grafts or in aneurysm repair (especially the aorta)
• Neurosurgery: as a dura mater substitute patch to help prevent cerebrospinal fluid (CSF) leakage
• Plastic and reconstructive surgery: reconstruction of damaged areas after tumor removal or trauma
• Prevention of visceral adhesions in abdominal or pelvic surgery
• Repair of cleft lip and palate (palate/lip cleft) in pediatric surgery
• Soft/hard tissue reconstruction in limb surgeries (hand, foot, knee, and tibia in orthopedics)